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CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states


AUTHORS

Leng KKun , Rose IVLIndigo V L , Kim HHyosung , Xia WWenlong , Romero-Fernandez WWilber , Rooney BBrendan , Koontz MMark , Li EEmmy , Ao YYan , Wang SShinong , Krawczyk MMitchell , Tcw JJulia , Goate AAlison , Zhang YYe , Ullian EMErik M , Sofroniew MVMichael V , Fancy SPJStephen P J , Schrag MSMatthew S , Lippmann ESEthan S , Kampmann MMartin . Nature neuroscience. 2022 10 27; ().

ABSTRACT