Skip to main content

Mechanobiology

Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration

AUTHORS

Colazo JMJuan M , Evans BCBrian C , Farinas AFAngel F , Al-Kassis SSalam , Duvall CLCraig L , Thayer WPWesley P . Tissue engineering. Part B, Reviews. 2019 8 2; 25(4). 259-290

ABSTRACT

IMPACT STATEMENT: The use of autologous tissue in the reconstruction of tissue defects has been the gold standard. However, current standards still face many limitations and complications. Improving patient outcomes and quality of life by addressing these barriers remain imperative. This article provides historical perspective, covers the major limitations of current standards of care, and reviews recent advances and future prospects in applied bioengineering in the context of tissue reconstruction, replacement, and regeneration.