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Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer.


AUTHORS

Liedtke AJAndy J , Adeniji AO Adegoke O , Chen M Mo , Byrns MC Michael C , Jin Y Yi , Christianson DW David W , Marnett LJ Lawrence J , Penning TM Trevor M . Journal of medicinal chemistry. 2013 3 28; 56(6). 2429-46

ABSTRACT