Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics.
AUTHORS
Konkle
MEMary E ,
Blobaum
AL Anna L ,
Moth
CW Christopher W ,
Prusakiewicz
JJ Jeffery J ,
Xu
S Shu ,
Ghebreselasie
K Kebreab ,
Akingbade
D Dapo ,
Jacobs
AT Aaron T ,
Rouzer
CA Carol A ,
Lybrand
TP Terry P ,
Marnett
LJ Lawrence J .
Biochemistry. 2016 1 19; 55(2).
348-59
- PMID: 26704937[PubMed].
- PMCID: PMC4721528.