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The Jason MacGurn Lab

The Jason MacGurn Lab Publications

2019

CP Nielsen , KK Jerningan , NL Diggins , DJ Webb , JA MacGurn , USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification 2019 Jul 23;
S Lee , HC Ho , JM Tumolo , PC Hsu , JA MacGurn , Methionine triggers Ppz-mediated dephosphorylation of Art1 to promote cargo-specific endocytosis. 2019 Mar 4;

2017

Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin. Elife. 2017 ;
Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs. Molecular Biology of the Cell. 2017 Mar 15; 28 (9). 1271-1283

2013

Zhao Y , Macgurn JA , Liu M , Emr S , The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress. eLife. 2013 ; 2 e00459

2012

Manford AG , Stefan CJ , Yuan HL , Macgurn JA , Emr SD , ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Developmental cell. 2012 Dec 11; 23 (6). 1129-40
Ling Y , Stefan CJ , Macgurn JA , Audhya A , Emr SD , The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P₂ synthesis. The EMBO journal. 2012 Jun 29; 31 (13). 2882-94
MacGurn JA , Hsu PC , Emr SD , Ubiquitin and membrane protein turnover: from cradle to grave. Annual review of biochemistry. 2012 ; 81 231-59

2011

MacGurn JA , Hsu PC , Smolka MB , Emr SD , TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell. 2011 Nov 23; 147 (5). 1104-17

2008

Lin CH , MacGurn JA , Chu T , Stefan CJ , Emr SD , Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell. 2008 Nov 14; 135 (4). 714-25

2007

McLaughlin B , Chon JS , MacGurn JA , Carlsson F , Cheng TL , Cox JS , Brown EJ , A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS pathogens. 2007 Aug 3; 3 (8). e105
Greenstein AE , MacGurn JA , Baer CE , Falick AM , Cox JS , Alber T , M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS pathogens. 2007 Apr ; 3 (4). e49
MacGurn JA , Cox JS , A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system. Infection and immunity. 2007 Jun ; 75 (6). 2668-78

2005

MacGurn JA , Raghavan S , Stanley SA , Cox JS , A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis. Molecular microbiology. 2005 Sep ; 57 (6). 1653-63