{"id":3597,"date":"2025-07-11T09:55:13","date_gmt":"2025-07-11T14:55:13","guid":{"rendered":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/?p=3597"},"modified":"2025-07-11T09:55:13","modified_gmt":"2025-07-11T14:55:13","slug":"neumora-therapeutics-announces-initiation-of-phase-1-clinical-study-of-m4-positive-allosteric-modulator-nmra-861","status":"publish","type":"post","link":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/2025\/07\/11\/neumora-therapeutics-announces-initiation-of-phase-1-clinical-study-of-m4-positive-allosteric-modulator-nmra-861\/","title":{"rendered":"Neumora Therapeutics Announces Initiation of Phase 1 Clinical Study of M4 Positive Allosteric Modulator NMRA-861"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-3598 size-medium alignleft\" src=\"https:\/\/cdn.vanderbilt.edu\/t2-main\/lab-prd\/wp-content\/uploads\/sites\/116\/2025\/07\/1752002783695-300x169.jpg\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/cdn.vanderbilt.edu\/t2-main\/lab-prd\/wp-content\/uploads\/sites\/116\/2025\/07\/1752002783695-300x169.jpg 300w, https:\/\/cdn.vanderbilt.edu\/t2-main\/lab-prd\/wp-content\/uploads\/sites\/116\/2025\/07\/1752002783695-768x432.jpg 768w, https:\/\/cdn.vanderbilt.edu\/t2-main\/lab-prd\/wp-content\/uploads\/sites\/116\/2025\/07\/1752002783695.jpg 800w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<p class=\"\">\ud835\udc0d\ud835\udc0c\ud835\udc11\ud835\udc00-\ud835\udfd6\ud835\udfd4\ud835\udfcf, a novel muscarinic M4 positive allosteric modulator (PAM) discovered at the Warren Center for Neuroscience Drug Discovery (WCNDD), has entered Phase 1 clinical trials in collaboration with <a href=\"https:\/\/www.linkedin.com\/company\/neumora\/\" target=\"_self\"><strong>Neumora<\/strong><\/a> Therapeutics.<\/p>\n<p class=\"\"><a href=\"https:\/\/ir.neumoratx.com\/news-releases\/news-release-details\/neumora-therapeutics-announces-initiation-phase-1-clinical-study\" target=\"_blank\" rel=\"noopener\">Read the Press release here \u2192<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ud835\udc0d\ud835\udc0c\ud835\udc11\ud835\udc00-\ud835\udfd6\ud835\udfd4\ud835\udfcf, a novel muscarinic M4 positive allosteric modulator (PAM) discovered at the Warren Center for Neuroscience Drug Discovery (WCNDD), has entered Phase 1 clinical trials in collaboration with Neumora Therapeutics. Read the Press release here \u2192<\/p>\n","protected":false},"author":564,"featured_media":3598,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[30],"class_list":["post-3597","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-group-news","tag-news"],"acf":[],"jetpack_featured_media_url":"https:\/\/cdn.vanderbilt.edu\/t2-main\/lab-prd\/wp-content\/uploads\/sites\/116\/2025\/07\/1752002783695.jpg","jetpack_shortlink":"https:\/\/wp.me\/pg6bwg-W1","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/posts\/3597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/users\/564"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/comments?post=3597"}],"version-history":[{"count":1,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/posts\/3597\/revisions"}],"predecessor-version":[{"id":3599,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/posts\/3597\/revisions\/3599"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/media\/3598"}],"wp:attachment":[{"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/media?parent=3597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/categories?post=3597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/lindsleylab\/wp-json\/wp\/v2\/tags?post=3597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}