Olivier Boutaud, Ph.D.
Research Associate Professor
Senior Director of DMPK
- : olivier.boutaud@vanderbilt.edu
- : (615) 875-9772
- :
201 Cool Springs Innovation Park
Vanderbilt University/WCNDD
393 Nichol Mill Lane, Room 2005
Franklin, Tennessee - 37067
Education
Universite Louis Pasteur, Strasbourg, France, 1990
BS Biochemistry
Universite Louis Pasteur, Strasbourg, France, 1994
Ph.D. Molecular and Cellular Pharmacology
Biosketch and Research Interests
Olivier Boutaud earned his Ph.D. in molecular pharmacology from the Université Louis Pasteur in Strasbourg, France. After a post-doctoral position at Vanderbilt University in Nashville, USA, he joined the Faculty in the Division of Clinical Pharmacology at Vanderbilt. There, he spent 20 years studying the pharmacology of NSAIDs. During this time, he discovered a new platelet phenotype associated with high reactivity and led a clinical study to assess this phenotype as a possible marker for high risk for heart attack. He was also associated with several clinical studies investigating the effects of paracetamol, aspirin and resveratrol in neurological and cardiovascular disorders.
Another interest of Olivier was the involvement of reactive dicarbonyls in neurodegenerative disorders like Alzheimer’s disease. This work culminated with Olivier leading a phase 1 clinical study investigating the safety of a natural scavengers of reactive dicarbonyl in humans. In 2020, Olivier moved to the Warren Center for Neuroscience Drug Discovery at Vanderbilt University, where he directs the laboratory of drug metabolism and pharmacokinetics (DMPK). He currently serves as the Senior Director of DMPK for the Warren Center. Olivier is the author of over 90 research and review publications and has contributed to 8 patents.