Elizabeth Childress, Ph.D.
Drug Discovery Scientist I
B.S. | The College of William and Mary, 2015 Chemistry |
Ph.D. | Virginia Tech, 2017 Organic Chemistry |
Phone: (615) 322-7415
Fax: (615) 778-1414
Email: elizabeth.s.childress@vanderbilt.edu
Location: Cool Springs Innovation Park
Mailing Address:
Vanderbilt University/VCNDD
Cool Springs Innovation Park
393 Nichol Mill Lane, Room 1000
Franklin, TN 37067
Biosketch and Research Interests
Beth joined the Lindsley lab as a postdoctoral research fellows in July 2017 and is currently working on developing novel negative allosteric modulators for the metabotropic glutamate receptor mGluR2, in addition to working on a collaboration beteween VCNDD and Ono Pharmaceuticals. Beth’s research interests include medicinal chemistry and synthetic organic chemistry.
Selected Publications
Childress, E.S.; Kharel, Y.; Brown, A.M.; Bevan, D.R.; Lynch, K.R.; Santos, W.L. ‘Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2-Selective Inhibitors: Design, Synthesis, and In Vivo Activity’ Journal of Medicinal Chemistry (2017); 60(9): 3933-3957. {DOI: 10.1021/acs.jmedchem.7b00233; PMID: 2846646}
Congdon, M.D.; Childress, E.S.; Patwardhan, N.N.; Grumkowski, J.; Morris, E.A.; Kharel, Y.; Lynch, K.L.; Santos, W.L. ‘Structure-Activity Relationship Studies of the Lipophilic Tail Region of Sphingosine Kinase 2 Inhibitors’ Bioorganic & Medicinal Chemistry Letters (2015); 25(21): 4956-4960. {DOI: 10.1016/j.bmcl.2015.03.041; PMID: 25862200}