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Knapik Laboratory Website Publications

2020

Unlu G , Qi X , Gamazon ER , Melville DB , Patel N , Rushing AR , Hashem M , Al-Faifi A , Chen R , Li B , Cox NJ , Alkuraya FS , Knapik EW , Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies Nature medicine. 2020 Jan 13; 26 (1). 98-109

2019

Unlu G , Gamazon ER , Qi X , Levic DS , Bastarache L , Denny JC , Roden DM , Mayzus I , Breyer M , Zhong X , Konkashbaev AI , Rzhetsky A , Knapik EW , Cox NJ , GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish American journal of human genetics. 2019 Feb 28; 104 (3). 503-519

2017

Hockman D , Burns AJ , Schlosser G , Gates KP , Jevans B , Mongera A , Fisher S , Unlu G , Knapik EW , Kaufman CK , Mosimann C , Zon LI , Lancman JJ , Dong PDS , Lickert H , Tucker AS , Baker CV , Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes eLife. 2017 Apr 7; 6
Cox NJ , Unlu G , Bisnett BJ , Meister TR , Condon BM , Luo PM , Smith TJ , Hanna M , Chhetri A , Soderblom EJ , Audhya A , Knapik EW , Boyce M , Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway Biochemistry. 2017 Dec 15; 57 (1). 91-107
Luderman LN , Unlu G , Knapik EW , Zebrafish Developmental Models of Skeletal Diseases Current topics in developmental biology. 2017 Jan 4; 124 81-124

2016

Müller II , Knapik EW , Hatzopoulos AK , Expression of the protein related to Dan and Cerberus gene–prdc–During eye, pharyngeal arch, somite, and swim bladder development in zebrafish Developmental dynamics : an official publication of the American Association of Anatomists. 2016 Oct ; 235 (10). 2881-8

2015

Levic DS , Minkel JR , Wang WD , Rybski WM , Melville DB , Knapik EW , Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease Journal of molecular medicine (Berlin, Germany). 2015 Jan 07; 93 (2). 165-76
Zou P , Wu SY , Koteiche HA , Mishra S , Levic DS , Knapik E , Chen W , Mchaourab HS , A conserved role of αA-crystallin in the development of the zebrafish embryonic lens Experimental eye research. 2015 Jul 4; 138 104-13

2014

Niu X , Hong J , Zheng X , Melville DB , Knapik EW , Meng A , Peng J , The nuclear pore complex function of Sec13 protein is required for cell survival during retinal development The Journal of biological chemistry. 2014 Mar 13; 289 (17). 11971-85

2013

Lee RT , Knapik EW , Thiery JP , Carney TJ , An exclusively mesodermal origin of fin mesenchyme demonstrates that zebrafish trunk neural crest does not generate ectomesenchyme Development (Cambridge, England). 2013 Jun 05; 140 (14). 2923-32
Venkateswaran A , Sekhar KR , Levic DS , Melville DB , Clark TA , Rybski WM , Walsh AJ , Skala MC , Crooks PA , Knapik EW , Freeman ML , The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development Cancer research. 2013 Nov 18; 74 (1). 38-43
Unlu G , Levic DS , Melville DB , Knapik EW , Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases The international journal of biochemistry & cell biology. 2013 Dec 09; 47 57-67

2012

Müller II , Melville DB , Tanwar V , Rybski WM , Mukherjee A , Shoemaker MB , Wang WD , Schoenhard JA , Roden DM , Darbar D , Knapik EW , Hatzopoulos AK , Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm Disease models & mechanisms. 2012 Dec 07; 6 (2). 332-41

2011

Melville DB , Knapik EW , Traffic jams in fish bones: ER-to-Golgi protein transport during zebrafish development Cell adhesion & migration. 2011 Mar 01; 5 (2). 114-8
Liu D , Wang WD , Melville DB , Cha YI , Yin Z , Issaeva N , Knapik EW , Yarbrough WG , Tumor suppressor Lzap regulates cell cycle progression, doming, and zebrafish epiboly Developmental dynamics : an official publication of the American Association of Anatomists. 2011 Apr 26; 240 (6). 1613-25
Melville DB , Montero-Balaguer M , Levic DS , Bradley K , Smith JR , Hatzopoulos AK , Knapik EW , The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis Disease models & mechanisms. 2011 Jul 04; 4 (6). 763-76
Wang WD , Melville DB , Montero-Balaguer M , Hatzopoulos AK , Knapik EW , Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population Developmental biology. 2011 Sep 22; 360 (1). 173-85

2010

Sarmah S , Barrallo-Gimeno A , Melville DB , Topczewski J , Solnica-Krezel L , Knapik EW , Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis PloS one. 2010 Apr 28; 5 (4). e10367

2008

Granero-Moltó F , Sarmah S , O'Rear L , Spagnoli A , Abrahamson D , Saus J , Hudson BG , Knapik EW , Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development The Journal of biological chemistry. 2008 Apr 18; 283 (29). 20495-504

2007

Bradley KM , Elmore JB , Breyer JP , Yaspan BL , Jessen JR , Knapik EW , Smith JR , A major zebrafish polymorphism resource for genetic mapping Genome biology. 2007 ; 8 (4). R55

2006

Montero-Balaguer M , Lang MR , Sachdev SW , Knappmeyer C , Stewart RA , De La Guardia A , Hatzopoulos AK , Knapik EW , The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish Developmental dynamics : an official publication of the American Association of Anatomists. 2006 Dec ; 235 (12). 3199-212
Lang MR , Lapierre LA , Frotscher M , Goldenring JR , Knapik EW , Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation Nature genetics. 2006 Sep 17; 38 (10). 1198-203

2004

Barrallo-Gimeno A , Holzschuh J , Driever W , Knapik EW , Neural crest survival and differentiation in zebrafish depends on mont blanc/tfap2a gene function Development (Cambridge, England). 2004 Feb 25; 131 (7). 1463-77

Kucenas S , Wang WD , Knapik EW , Appel B , A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord The Journal of neuroscience : the official journal of the Society for Neuroscience. ; 29 (48). 15187-94
Bradley KM , Breyer JP , Melville DB , Broman KW , Knapik EW , Smith JR , An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci G3 (Bethesda, Md.). ; 1 (1). 3-9
Vacaru AM , Unlu G , Spitzner M , Mione M , Knapik EW , Sadler KC , In vivo cell biology in zebrafish – providing insights into vertebrate development and disease Journal of cell science. ; 127 (Pt 3). 485-95
Tanwar V , Bylund JB , Hu J , Yan J , Walthall JM , Mukherjee A , Heaton WH , Wang WD , Potet F , Rai M , Kupershmidt S , Knapik EW , Hatzopoulos AK , Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway Stem cells (Dayton, Ohio). ; 32 (7). 1774-88