Welcome to the Hinton Lab group website. We use a broad range of tools to explore mechanisms that regulate molecular transfer between and changes in morphology of the mitochondria and endoplasmic reticulum (ER) and how these mechanisms are altered during the pathophysiological states of diabetes, obesity, and cardiovascular disease.<\/p>\n \n
Technical approaches employed in the lab target cellular physiology, biophysics, structural biology, molecular pharmacology, and cell signaling, and we translate our research from the bench to the bedside. The Hinton group applies techniques such as primary cell isolation, bioinformatics programming for large data sets,\u00a0in vitro<\/em>\u00a0exercise, confocal\/stimulated emission depletion (STED) microscopy, transmission electron microscopy (TEM), 3D electron microscopy, and various types of image analysis. Additionally, we use human primary cells and cell lines and mouse and fly model organisms to delineate pathophysiological states.<\/p>\n \n Trainees have the opportunity to practice career development in the laboratory and in the community. Career development is a long-term means of continual learning, work, leisure (i.e. work-life-balance), and transitions to move toward an individually determined and evolving chosen goal. We have four laboratory meetings every month, held Tuesdays at 1 p.m., during which we focus for 10-15 minutes on career advice, grantsmanship, and progress toward personal growth.<\/p>\n Further, each Tuesday’s laboratory meeting is distinctly different:<\/p>\n \n Week 1:<\/strong>\u00a0This meeting will be research-based, where a member of the laboratory discusses his\/her\/their progress. The Hinton laboratory’s goal is to encourage and uplift trainees. The Hinton laboratory strongly emphasizes solidarity and promotes novel interdisciplinary collaborations to foster innovation. Notably, Hinton laboratory members will work hard and bolster one another in the crucibles of scientific research and life.<\/p>\n \n We hope our website conveys a sense of the excitement we feel for our research and the character of the talented people who make up our team. We also hope you will develop an appreciation for the unique environment at Vanderbilt, which comprises outstanding facilities, dynamic research groups, and productive collaborations. Don’t hesitate to get in touch with us if you have any questions about the Hinton Laboratory or Vanderbilt University.<\/p>\n \n\n","protected":false},"excerpt":{"rendered":" Welcome to the Hinton Lab group website. We use a broad range of tools to explore mechanisms that regulate molecular transfer between and changes in morphology of the mitochondria and endoplasmic reticulum (ER) and how these mechanisms are altered during the pathophysiological states of diabetes, obesity, and cardiovascular disease. Technical approaches employed in the lab […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-2","page","type-page","status-publish","hentry"],"acf":[],"ACF":{"topper_style":"default","topper_overline":"","topper_title":"","topper_intro":"","default_topper_background_type":"none","footer_style":"standard","recirculation_style":"none","nav_menu":"","nav_menu_secondary":"no","page_style_option":"details","page_theme_option":"light","page_class_name":"","page_jumplinks_option":"no"},"jetpack_shortlink":"https:\/\/wp.me\/Pd98bx-2","jetpack-related-posts":[{"id":1655,"url":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/?post_type=acf-field-group&p=1655","url_meta":{"origin":2,"position":0},"title":"Home Page Options","author":"Jeffrey Kirkwood","date":"March 30, 2026","format":false,"excerpt":"home-page-options","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1877,"url":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/home-backup\/","url_meta":{"origin":2,"position":1},"title":"Home backup","author":"Gobinath Mani","date":"April 7, 2026","format":false,"excerpt":"Welcome to the Hinton Lab group website. We use a broad range of tools to explore mechanisms that regulate molecular transfer between and changes in morphology of the mitochondria and endoplasmic reticulum (ER) and how these mechanisms are altered during the pathophysiological states of diabetes, obesity, and cardiovascular disease. Technical\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":103,"url":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/about\/","url_meta":{"origin":2,"position":2},"title":"Biosketch","author":"Stephen Doster","date":"June 14, 2021","format":false,"excerpt":"Info Text - Right Hand Column PlaceholderRefresh After Saving to Remove BiosketchBiosketchCurrent Speaking EngagementsPast Speaking EngagementsPast Speaking Engagements Photos Dr. Antentor Hinton, Jr. Dr. Antentor Hinton, Jr.\u00a0is a tenure-track Assistant Professor in the Department of Molecular Physiology and Biophysics in Vanderbilt University's School of Medicine Basic Sciences, a member of\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":111,"url":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/research\/","url_meta":{"origin":2,"position":3},"title":"Research","author":"Stephen Doster","date":"June 14, 2021","format":false,"excerpt":"Info Text - Right Hand Column PlaceholderRefresh After Saving to Remove Hinton Lab NewsHinton Lab hosts 2nd Annual Brazilian Scientific Journey on Mitochondrial DeregulationHinton Lab Featured in Brazilian NewsSample Research TalkVideo Dr. Antentor Hinton Jr, has made extensive use of Amira Software as part of his lab's work in mitochondrial\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":374,"url":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/about\/speaking-engagements\/","url_meta":{"origin":2,"position":4},"title":"Current Speaking Engagements","author":"Stephen Doster","date":"August 6, 2021","format":false,"excerpt":"Info Text - Right Hand Column PlaceholderRefresh After Saving to Remove BiosketchBiosketchCurrent Speaking EngagementsPast Speaking EngagementsPast Speaking Engagements Photos Upcoming Talks Stony Brook University,\u00a0Department of Microbiology & Immunology, \"Guiding Greatness: Effective Leadership through Mentorship and Training\" (Jun 2024) 6th World Aging And Rejuvenation Conference,\u00a0Virtual, \"Mitochondrial Changes in the Aging Process\"\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/lab.vanderbilt.edu\/hinton-lab\/wp-content\/uploads\/sites\/150\/2026\/04\/Hinton_speaking-engagement-300x300.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":1122,"url":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/research-reviews-and-research-commentaries\/","url_meta":{"origin":2,"position":5},"title":"Research Reviews and Research Commentaries","author":"Stephen Doster","date":"July 12, 2023","format":false,"excerpt":"Research Reviews & Perspectives Afolabi, J., Laffer, C.L., Beasley, H.,\u00a0Hinton, A., Masenga, S.K., Kirabo. A. Reflecting on current understanding of Salt-sensitivity of Blood Pressure: Historical and future perspectives. (Circulation Research, in Press) Demirci, M.,\u00a0Hinton, A.,\u00a0& Kirabo, A. (2024). Dendritic cell epithelial sodium channel induced inflammation and salt-sensitive hypertension.\u00a0Current opinion in\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/pages\/2","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/comments?post=2"}],"version-history":[{"count":19,"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/pages\/2\/revisions"}],"predecessor-version":[{"id":1759,"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/pages\/2\/revisions\/1759"}],"wp:attachment":[{"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/media?parent=2"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/hinton-lab\/wp-json\/wp\/v2\/tags?post=2"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Career Development<\/h2>\n
\nWeek 2:<\/strong>\u00a0Two laboratory members will present journal clubs.
\nWeek 3:<\/strong>\u00a0We will work on grantsmanship, fellowship applications, and opportunities related to writing.
\nWeek 4:<\/strong>\u00a0We will build individual lab members’ brand and review each of the Hinton Lab member’s development plans. A lab member will present his\/her\/their research in progress.
\nWeek 5:<\/strong>\u00a0We will participate in a team-building activity that includes a celebration of our successes.\n \n Mission<\/h2>\n