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Bridget Collins

Rotation student, August 2016

Bridget received her BA in biochemistry from Columbia University and is currently a second-year MSTP student at Vanderbilt.

Working with graduate student Nicki Perry, she is focusing on mapping the interaction of arrestin-3 with downstream effector kinases. Using in vitro pull-down assays, she is assessing the binding profile of a series of MBP fusion peptides, derived from arrestin-3, with ERK2. This information will help elucidate the structural basis of arrestin scaffolding of the kinase cascade leading to the activation of ERK1/2, which promote cell survival.