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Publications

2022

Conwell SC, Cranford MT, Kavlashvili T, Dewar JM, Replication fork collapse in vitro using Xenopus egg extracts Methods in enzymology. 2022 Apr 09; 672 317-338
Campos V, Greer H, Heintzman R, Kavlashvili Tamar, McDonald Hayes, Rose Lindsey, Eichman F., Dewar M., RTEL1 and MCM10 overcome topological stress during vertebrate replication termination bioRxiv. 2022 Aug 2;
Kavlashvili Tamar, Dewar James, Replication Fork Uncoupling Causes Nascent Strand Degradation and Fork Reversal bioRxiv. 2022 Aug 1;
Van Ravenstein SX, Mehta KP, Kavlashvili T, Byl JAW, Zhao R, Osheroff N, Cortez D, Dewar JM, Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms The EMBO journal. 2022 May 16; 41 (12) e110632

2021

Vrtis KB, Dewar JM, Chistol G, Wu RA, Graham TGW, Walter JC, Single-strand DNA breaks cause replisome disassembly Molecular cell. 2021 Jan 22; 81 (6) 1309-1318.e6

2019

Heintzman DR, Campos LV, Byl JAW, Osheroff N, Dewar JM, Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination Cell reports. 2019 Oct 8; 29 (2) 422-436.e5

2017

Dewar JM, Walter JC, Mechanisms of DNA replication termination. Nature reviews. Molecular cell biology. 2017 Aug 18 (8) 507-516
Dewar JM, Low E, Mann M, Räschle M, Walter JC, CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication terminat… Genes & development. 2017 Feb 1; 31 (3) 275-290

2015

Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC, DNA interstrand cross-link repair requires replication-fork convergence. Nature structural & molecular biology. 2015 Mar 22 (3) 242-7
Dewar JM, Budzowska M, Walter JC, The mechanism of DNA replication termination in vertebrates. Nature. 2015 Sep 17; 525 (7569) 345-50

2014

Castillo Bosch P, Segura-Bayona S, Koole W, van Heteren JT, Dewar JM, Tijsterman M, Knipscheer P, FANCJ promotes DNA synthesis through G-quadruplex structures. The EMBO journal. 2014 Nov 3; 33 (21) 2521-33
Duxin JP, Dewar JM, Yardimci H, Walter JC, Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell. 2014 Oct 9; 159 (2) 346-57

2013

Dewar JM, Walter JC, Chromosome biology: conflict management for replication and transcription. Current biology : CB. 2013 Mar 4; 23 (5) R200-2

2012

Dewar JM, Lydall D, Simple, non-radioactive measurement of single-stranded DNA at telomeric, sub-telomeric, and genomic … Methods in molecular biology (Clifton, N.J.). 2012 920 341-8

2011

Weile J, Pocock M, Cockell SJ, Lord P, Dewar JM, Holstein EM, Wilkinson D, Lydall D, Hallinan J, Wipat A, Customizable views on semantically integrated networks for systems biology. Bioinformatics (Oxford, England). 2011 May 1; 27 (9) 1299-306

2010

Dewar JM, Lydall D, Telomere replication: Mre11 leads the way. Molecular cell. 2010 Jun 25; 38 (6) 777-9
Dewar JM, Lydall D, Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. The EMBO journal. 2010 Dec 1; 29 (23) 4020-34