DEWAR Lab

Conwell SC , Cranford MT , Kavlashvili T , Dewar JM , Replication fork collapse in vitro using Xenopus egg extracts Methods in enzymology. 2022 Apr 09; 672 317-338

• PMID: 35934482 [PubMed].

Campos V , Greer H , Heintzman R , Kavlashvili Tamar , McDonald Hayes , Rose Lindsey , Eichman F. , Dewar M. , RTEL1 and MCM10 overcome topological stress during vertebrate replication termination bioRxiv. 2022 Aug 2;

Kavlashvili Tamar , Dewar James , Replication Fork Uncoupling Causes Nascent Strand Degradation and Fork Reversal bioRxiv. 2022 Aug 1;

Van Ravenstein SX , Mehta KP , Kavlashvili T , Byl JAW , Zhao R , Osheroff N , Cortez D , Dewar JM , Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms The EMBO journal. 2022 May 16; 41 (12). e110632

• PMID: 35578785 [PubMed].

Vrtis KB , Dewar JM , Chistol G , Wu RA , Graham TGW , Walter JC , Single-strand DNA breaks cause replisome disassembly Molecular cell. 2021 Jan 22; 81 (6). 1309-1318.e6

• PMID: 33484638 [PubMed].

Heintzman DR , Campos LV , Byl JAW , Osheroff N , Dewar JM , Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination Cell reports. 2019 Oct 8; 29 (2). 422-436.e5

• PMID: 31597101 [PubMed].
• PMCID: PMC6919565.

Dewar JM , Low E , Mann M , Räschle M , Walter JC , CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication terminat… Genes & development. 2017 Feb 1; 31 (3). 275-290

• PMID: 28235849 [PubMed].
• PMCID: PMC5358724.

Dewar JM , Walter JC , Mechanisms of DNA replication termination. Nature reviews. Molecular cell biology. 2017 Aug ; 18 (8). 507-516

• PMID: 28537574 [PubMed].

Dewar JM , Budzowska M , Walter JC , The mechanism of DNA replication termination in vertebrates. Nature. 2015 Sep 17; 525 (7569). 345-50

• PMID: 26322582 [PubMed].
• PMCID: PMC4575634.
• NIHMSID: NIHMS704630

Zhang J , Dewar JM , Budzowska M , Motnenko A , Cohn MA , Walter JC , DNA interstrand cross-link repair requires replication-fork convergence. Nature structural & molecular biology. 2015 Mar ; 22 (3). 242-7

• PMID: 25643322 [PubMed].
• PMCID: PMC4351167.
• NIHMSID: NIHMS649962

Duxin JP , Dewar JM , Yardimci H , Walter JC , Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell. 2014 Oct 9; 159 (2). 346-57

• PMID: 25303529 [PubMed].
• PMCID: PMC4229047.
• NIHMSID: NIHMS633322

Castillo Bosch P , Segura-Bayona S , Koole W , van Heteren JT , Dewar JM , Tijsterman M , Knipscheer P , FANCJ promotes DNA synthesis through G-quadruplex structures. The EMBO journal. 2014 Nov 3; 33 (21). 2521-33

• PMID: 25193968 [PubMed].
• PMCID: PMC4282361.

Dewar JM , Walter JC , Chromosome biology: conflict management for replication and transcription. Current biology : CB. 2013 Mar 4; 23 (5). R200-2

• PMID: 23473562 [PubMed].

Dewar JM , Lydall D , Simple, non-radioactive measurement of single-stranded DNA at telomeric, sub-telomeric, and genomic … Methods in molecular biology (Clifton, N.J.). 2012 ; 920 341-8

• PMID: 22941615 [PubMed].

Dewar JM , Lydall D , Similarities and differences between “uncapped” telomeres and DNA double-strand breaks. Chromosoma. 2012 Apr ; 121 (2). 117-30

• PMID: 22203190 [PubMed].

Weile J , Pocock M , Cockell SJ , Lord P , Dewar JM , Holstein EM , Wilkinson D , Lydall D , Hallinan J , Wipat A , Customizable views on semantically integrated networks for systems biology. Bioinformatics (Oxford, England). 2011 May 1; 27 (9). 1299-306

• PMID: 21414991 [PubMed].
• PMCID: PMC3077072.

Dewar JM , Lydall D , Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. The EMBO journal. 2010 Dec 1; 29 (23). 4020-34

• PMID: 21045806 [PubMed].
• PMCID: PMC3020640.

Dewar JM , Lydall D , Telomere replication: Mre11 leads the way. Molecular cell. 2010 Jun 25; 38 (6). 777-9

• PMID: 20620949 [PubMed].