Gurevich Lab

Evan Curtin is a rising senior (class of 2022) majoring in Neuroscience and minoring in Chinese Language & Culture. He is from Wayland, MA, and came to Nashville to escape the cold winters and experience all that Vanderbilt’s campus has to offer. In his free time, he enjoys playing tennis and exploring new coffee shops around Nashville.

Evan volunteers in the lab since October 2020. Evan is performing comprehensive mutagenesis of the finger loop of arrestin-3. Based on existing structures of the arrestin-receptor complex and our recent study of arrestin-1 finger loop, we expect the finger loop of all arrestins to serve as the sensor of receptor activation. The mutants Evan is generating will be used to test this hypothesis using in-cell arrestin-receptor interaction assay.